BNA FISH Probe for Chromosomal DNA Detection
Even though fluorescence in situ hybridization - FISH probe has been widely used in cytogenetic applications, it is generally time-consuming and lack of sensitivity and resolution. Bio-Synthesis's high...
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Oligo Biotin Labeling
Biotinylated Oligonucleotides Bio-Synthesis offers biotinylated oligonucleotides for RNA and DNA detection or isolation application due to its high affinity toward strepatvidin. Biotinylated...
View ArticleMethylated Lysine for Post-translational Modification
Post-translational modifications of proteins play critical roles in the regulation and function of many known biological processes. Proteins can be post-translationally modified in many different ways,...
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Oligonucleotide Analyzer / Calculator.
Oligonucleotide AnalyzerThe quantity of an oligonucleotide usually is given as its total optical density (OD value), as amount of substance (nmol) or as its available mass (μg). The OD value is...
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Template optimization using In Vitro Transcription.
Template optimization using In Vitro TranscriptionBio-Synthesis provides enzymatic long RNA synthesis using transcription from DNA template. In vitro transcribed RNA can be used as control template for...
View ArticleExtinction Coefficients and Fluorescence
EXTINCTION COEFFICIENTS AND FLUORESCENCE DATACalculate extinction coefficient of an oligo by either summing up the extinction coefficients of the individual bases times their number of occurrences. Or...
View ArticlePalmitoylated Peptides: Pam2Cys-peptides and Pam3Cys-peptides.
Pam2Cys-peptides and Pam3Cys-peptides are Palmitoylated Peptides known to activate the immune system through toll like receptors. Short peptide sequences play a major role in immune recognition. A...
View ArticleRNA Transcription
Transcription refers to the transfer of genetic code information from one kind of nucleic acid to another and to the process by which a base sequence of messenger RNA is synthesized by an RNA...
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Amino Acid Analysis / Testing
Amino Acid Analysis / Testing refers to the quantitative analysis of either free amino acids or amino acids released from proteins via hydrolysis present in biological samples such as blood, plasma,...
View ArticleImproving the stability of an RNA sequence
Thioate groups can be incorporate in the RNA linkages between two bases. This approach is dependent on the specific application. We recommend the incorporating of BNA monomers into synthetic...
View ArticleVasopressin receptors and jet lag
Can jet lag be avoided? No, not yet, but recent research indicates that there is hope for a cure in the near future. The neuropeptide, arginine vasopressin, appears to be an important part of...
View ArticleAmino Acid Analysis of Plasma.
Amino acid analysis of plasma metabolites.Amino acid analysis is an important tool for the analysis of free amino acids and other similar biomolecules that contain primary and secondary amino groups...
View ArticleConjugate Vaccines.
To elicit an immune response against protein/peptide antigens lacking T-cell epitopes, or against non-peptidic antigens, such as oligosaccharides, there is a need to conjugate these compounds...
View ArticleSpectrophotometric conversions of protein and nucleic acids
This content provides several useful information of common biological constants and conversions. You can use these tables to aid your DNA/RNA/protein quantification, electrophoresis gel preparation,...
View ArticleL-Glutamic Acid, a micronutrient
Glutamic acid (Glu, E) is an amino acid with the formula HOOC-CH2-CH2-CH(NH2)-COOH and has a molecular weight of 147.13 g mol−1. The L-isomer is one of the basic building blocks of proteins. Glutamic...
View ArticleTaurine
Taurine, also called 2-aminoethanesulfonic acid, is a sulfonic acid of the formula HOSO2-CH2-CH2-NH2 and has a molecular weight of 125.15 g mol−1 that is widely distributed in animal tissues. It is...
View ArticleDoxorubicin Conjugates
Doxorubicin is an anthracycline antibiotic used in cancer chemotherapy, which is also being evaluated as an antiviral agent. Two different mechanisms have been proposed to explain doxorubicin...
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DNA Methylation Analysis Techniques in Epigenetics
DNA Methylation Analysis Techniques in EpigeneticsBy Klaus D. Linse After sequencing the human genome scientists began to realize that just knowing the genetic information of an individual is not...
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ABT-510 Peptide
Bio-Synthesis provides ABT-510 peptide syntehsis, this synthetic peptide that mimics the anti-angiogenic activity of the endogenous protein thrombospondin-1 (TSP-1). The systematic name for the ABT-510...
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Nanoparticle Applications
Nanoparticles in Biology and MedicineA brief history of firsts in nanotechnology: Nanotechnology started in 1959 when Feynman gave an after-dinner talk describing molecular machines built with atomic...
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