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Method of Oligonucleotide Purification
Method of Oligonucleotide PurificationMethod of Oligonucleotide purification depends on three key factors:Oligonucleotide lengthApplicationModificationsThe first factor is the length of an...
View ArticleAc-SDKP peptide (also known as seraspenide or goralatide)
The synthetic tetrapeptide Ac-SDKP, also called seraspenide or goralatide, has the chemical structure 1-(N2-(N-(N-acetyl-L-seryl)-L-alpha-aspartyl)-L-lysyl)-L-proline, the molecular formula...
View ArticleSize Exclusion Chromatography
Size exclusion chromatography (SEC) is a standard separation technique for determining molar mass averages and molar mass distributions of polymers such as whole proteins, protein conjugates, peptides,...
View ArticleNeuropeptides for Neuroscience Research
Neuropeptides for Neuroscience ResearchOne of the greatest challenges in neuroscience research is to understand how biologically active molecules such as small molecules and peptides function at...
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Peptide Design for Immunization using Multiple Antigen Peptides
How to design peptides useful for immunization using multiple antigen peptides (MAPs)The design of peptides to generate antibodies against protein epitopes is still considered an art. However,...
View ArticlePropionylated and Acetylated Peptides
Many posttranslational modifications have been identified on functional groups of amino acid side chains in many proteins and peptides over the years. In particularly, protein acetylation has been...
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SABI
Switch mode to "source" to view source code for a mix of text and images. Images must be placed on the Amazon Server in the folder /biosyn35/images/userfiles/image/A brief history of firsts in...
View ArticleHybrid Peptides
The term "hybrid" in biology is defined as "the offspring of two plants or animals of different species or varieties, such as a mule, which is a hybrid of a donkey and a horse. Other examples of...
View ArticleNative PAGE / Gel Electrophoresis Methods
Native gelelectrophoresis uses native or non-denaturing gels for the analysis of proteins in their folded, native state. The electrophoretic mobility of an intact protein is depended on its...
View ArticleLocked Nucleic Acids (LNA) Vs. Bridged Nucleic Acids (BNA)
There are numerous chemical modifications commonly done to synthetic oligonucleotides for a variety of reasons. Some of these reasons can be to increase stability of the phosphate backbone, adjust...
View ArticleClick Chemistry
Bio-Synthesis offers several types of azide, alkyne, or copper free dibenzo-cycloocytne (DBCO) modifiers to be introduced at the 5’, 3’, or internal positions during chemical synthesis. The reaction...
View ArticleCRISPR-Cas Systems
There are three types of CRISPR-Cas systems, type I, II and III.Type I and III CRISPR/Cas systems share specialized Cas endo-nucleases that process the pre-crRNAs. After maturation, each crRNA...
View ArticleGlycosylated Peptide Synthesis
Bio-Synthesis provides glycosylated peptide synthesis by using Fmoc-glycosylated amino acids. Glycosylated amino acid derivatives of Asparagine, Serine, Threonine and Tyrosine. Glycosylated petpides...
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Methylene Blue Oligo Labeling
Bio-Synthesis offers methylene Blue (MB) oligo, peptide and protein labeling. Methylene blue (MB) label also known as Dimethylaminophenothiazin-5-ium chloride, has been use as redox indicator1,...
View ArticleFluorescent Base Analog for DNA or RNA Synthesis
Bio-Synthesis provides fluorescent nucleoside base oligonucleotide synthesis. These nucleoside base analog is highly dependent of the environment of teh base and the measurement of its fluorescence is...
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Amino Acid Analysis to elucidate Tryptophan Pathways
Amino Acid Analysis to elucidate Tryptophan Pathways By Klaus D. LinseModern automated amino acid analysis is considered to be the standard tool for quantitative analysis of metabolites of the...
View ArticleDolastatin Peptides
Dolastatin peptides belong to a group of cytotoxic anti-cancer depsipeptides derived from Dolabella auricularia also called the "wedge sea hare" or "Donsol" found in the Indian Ocean, the Western and...
View ArticleTherapeutic Peptides for Treating Cancer
Peptides, either natural or synthetic, have seen increased application as therapeutic agents in recent years. In 2012, in addition to almost 80 peptides on the market, approximately 200 more have been...
View ArticleAnticancer Peptides
Anticancer peptides are peptides that can be used as therapeutic agents to treat various cancers. A search of the U.S. National Institutes of the ClinicalTrials.gov database using the phrase...
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